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KMID : 0856920080110030136
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Journal of Hospice and Palliative Care
2008 Volume.11 No. 3 p.136 ~ p.139
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Epidural Morphine for Pain Control in Patients with Terminal Cancer in Hospice Ward
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Lee Jang-Eun
Kang Eu-Jin
Lee Ok-Kyung
Huh Ki-Hoon
Sim Byung-Yong
Kim Hoon-Kyo
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Abstract
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Purpose: Epidural morphine infusion has been used to control pain in cancer patients whose cancer pain can not be controlled high dose intravenous morphine injection. To study the effectiveness and side effects of epidural morphine for the treatment of cancer pain in terminal patients at Hospice Ward, we evaluated the change in morphine equivalent daily dose for effectiveness and complications of epidural morphine infusion.
Methods: We retrospectively analyzed 24 terminal cancer patients who were treated with continuous epidural morphine between 2001 and 2004 at Hospice Ward of St. Vincent’s Hospital.
Results: The median of baseline morphine equivalent daily dose was 615 mg, whereas the median dose of initial epidural morphine was 16 mg. The median of morphine daily equivalent daily dose dropped from 615 mg to 274 mg in one week after epidural morphine infusion therapy (P-value=0.000). The median survival from the time of the first catheter insertion was 35 days. In 6 patients, the catheter was removed due to complications, however the catheter was reinserted in 3 patients.
Conclusion: Cancer pain management by epidural morphine infusion is very effective method with low rate of severe complication.
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KEYWORD
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Cancer pain, Epidural morphine, Hospice ward
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